Pseudomonas aeruginosa PAO1 Gene: bioB
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ID: PA0500

Citations: [ Sanyal94 , Shaw98 , Gibson99 ]

Map Position: 559,644 -> 560,702 (nucleotides) 8.93 (centisomes)

Sequence Length: 1059 bp / 352 AAs

Products: biotin synthase

Click on product name to see summaries, citations and other data about the gene product and its function.

Reactions Catalyzed by Enzymes:
a sulfur donor + dethiobiotin = biotin

Pathways Involving Enzymes: biotin biosynthesis II

Gene-Reaction Schematic:

GO Terms:

MultiFun Terms: UNCLASSIFIED

Unification Links: PseudoCAP:PA0500

Gene Local Context (not to scale):

Transcription Unit:

Notes:


References

Gibson99: Gibson KJ, Pelletier DA, Turner IM (1999). "Transfer of sulfur to biotin from biotin synthase (BioB protein)." Biochem Biophys Res Commun 254(3);632-5. PMID: 9920791

Sanyal94: Sanyal I, Cohen G, Flint DH (1994). "Biotin synthase: purification, characterization as a [2Fe-2S]cluster protein, and in vitro activity of the Escherichia coli bioB gene product." Biochemistry 33(12);3625-31. PMID: 8142361

Shaw98: Shaw NM, Birch OM, Tinschert A, Venetz V, Dietrich R, Savoy LA (1998). "Biotin synthase from Escherichia coli: isolation of an enzyme-generated intermediate and stoichiometry of S-adenosylmethionine use." Biochem J 330 ( Pt 3);1079-85. PMID: 9494071


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