Pseudomonas aeruginosa PAO1 Gene: bioF

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ID: PA0501

Citations: [ Otsuka88 , Webster98 , Alexeev98 ]

Sequence Length: 1206 bp / 401 AAs

Products: 8-amino-7-oxononanoate synthase

Click on product name to see summaries, citations and other data about the gene product and its function.

Reactions Catalyzed by Enzymes:
L-alanine + 6-carboxyhexanoyl-CoA = CO₂ + Coenzyme A + 8-amino-7-oxononanoate

Pathways Involving Enzymes: biotin biosynthesis II

Gene-Reaction Schematic:

GO Terms:

Unification Links: PseudoCAP:PA0501

Gene Local Context (not to scale):

Transcription Unit:

Notes:

• A dashed baseline indicates that there is no high-quality evidence to confirm the extent of this transcription unit.
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References

Alexeev98: Alexeev D, Alexeeva M, Baxter RL, Campopiano DJ, Webster SP, Sawyer L (1998). "The crystal structure of 8-amino-7-oxononanoate synthase: a bacterial PLP-dependent, acyl-CoA-condensing enzyme." J Mol Biol 284(2);401-19. PMID: 9813126

Otsuka88: Otsuka AJ, Buoncristiani MR, Howard PK, Flamm J, Johnson C, Yamamoto R, Uchida K, Cook C, Ruppert J, Matsuzaki J (1988). "The Escherichia coli biotin biosynthetic enzyme sequences predicted from the nucleotide sequence of the bio operon." J Biol Chem 263(36);19577-85. PMID: 3058702

Webster98: Webster SP, Campopiano DJ, Alexeev D, Alexeeva M, Watt RM, Sawyer L, Baxter RL (1998). "Characterisation of 8-amino-7-oxononanoate synthase: a bacterial PLP-dependent, acyl CoA condensing enzyme." Biochem Soc Trans 26(3);S268. PMID: 9765987