Pseudomonas aeruginosa PAO1 Gene: nrdB

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ID: PA1155

Citations: [ Lewenza05 , Torrents06 , Elledge87 ]

Sequence Length: 1248 bp / 415 AAs

Products: NrdB, tyrosyl radical-harboring component of class Ia ribonucleotide reductase , subunit of ribonucleoside reductase

Click on product name to see summaries, citations and other data about the gene product and its function.

Reactions Catalyzed by Enzymes:
a 2'-deoxyribonucleoside diphosphate + an oxidized thioredoxin + H₂O + 2'-deoxyribonucleoside diphosphate = a ribonucleoside diphosphate + a reduced thioredoxin + ribonucleoside diphosphate

Gene-Reaction Schematic:

GO Terms:

Unification Links: PseudoCAP:PA1155

Gene Local Context (not to scale):

Transcription Unit:

Notes:

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References

Elledge87: Elledge SJ, Davis RW (1987). "Identification and isolation of the gene encoding the small subunit of ribonucleotide reductase from Saccharomyces cerevisiae: DNA damage-inducible gene required for mitotic viability." Mol Cell Biol 7(8);2783-93. PMID: 3313004

Lewenza05: Lewenza S, Gardy JL, Brinkman FS, Hancock RE (2005). "Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen." Genome Res 15(2);321-9. PMID: 15687295

Torrents06: Torrents E, Westman M, Sahlin M, Sjoberg BM (2006). "Ribonucleotide reductase modularity: Atypical duplication of the ATP-cone domain in Pseudomonas aeruginosa." J Biol Chem 281(35);25287-96. PMID: 16829681